Hello @dxcrestsyndrome2020, Welcome to Connect. I'm glad you found us. I don't have any personal experience but you are not alone and there are others who can share their experiences with you. You might want to join the following discussion to learn what others have found helpful:

-- Limited Scleroderma or CREST Syndrome: What helps?:
https://connect.mayoclinic.org/discussion/crest-syndrome/

Hi @dxcrestsyndrome2020

It's been so long since I first got sick (six years now), I no longer remember what they tested exactly.

I do know the doctor who tested for ANAs initially also tested for several other antibodies, but I'm not sure exactly which ones and they were all negative. The only test results that were consistently high were liver enzymes (AST, ALT, and gGT), blood pressure (at times over 200 systolic when I'd always previously had pretty low BP), and ANAs. They first tested for ANAs in April 2017 with results of 1:2560 “Mitotic II” pattern. The doctor said it must be an error so he re-tested two months later and the titer was 1:1280+ with “fine speckled” pattern. Do you know what type of ANA pattern you tested positive for?

I never did get a diagnosis, nor have I actually seen a doctor in years. My health gradually started to improve after the first couple of years and has continued to improve with time, gradual return to exercise, and a careful diet. At some point I made the decision not to try to find "answers" or get a diagnosis.

I'm glad to hear that turmeric has helped for you. Hopefully your road will be smooth from here on out!