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Invasive ductal carcinoma (IDC): Anyone else?

Breast Cancer | Last Active: Mar 24 10:10am | Replies (223)

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@elliej

Thanks Again for good advise. My rate of recurrence on the OncoType test is 4%. Did you say that you opted out of radiation? One of my concerns is the pathology report of Hyperplasic cells. The radiologist said radiation would Not affect those. That I don’t understand. Do you know anything about that? More confusion……

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Replies to "Thanks Again for good advise. My rate of recurrence on the OncoType test is 4%. Did..."

@elliej: Atypical ductal hyperplasia (see below) is not cancer yet so that may be why radiation doesn't affect it. Your Oncotype score was 16 but your risk of recurrence was 4%? Assuming this was with tamoxifen. That seems low for a score of 16 but there may be mitigating factors so that is an encouraging number. From googling:

Atypical ductal hyperplasia is a histologically borderline lesion that has some, but not all, of the features of ductal carcinoma in situ. Sometimes the distinction between Atypical ductal hyperplasia and ductal carcinoma in situ are simply defined on the number of ducts involved.
Pathology
Atypical ductal hyperplasia is a lesion with malignant potential. It lacks the strict criteria for ductal carcinoma in situ, with <2 ducts involved 3.

I think we all need to be careful in comparing our cases. @callalloo had DCIS (invasive), you have invasive ductal grade 1, I had invasive mixed ductal and lobular grade 3. All I can say is that if you feel trust on your doctor, move forward. If you don't, then get another opinion(s).

It sounds like you are ready to roll with radiation. Since you had a lumpectomy, that seems reasonable and your doc suggested it (though you have a choice of course). I really hope you give hormonal meds a good chance. Side effects change and ease up over time, in my experience, if not others'. I am around your age and get it!

I declined radiation but it was very site-specific and would not have affected distant recurrence rate or even risk of recurrence in other breast or another area of the same breast. The lumpecfomy was in my left breast and I was concerned about any possible radiation damage to my heart.

I don't know what hyperplasia cells are so can't shed any light on the effect of radiation on them. Don't hesitate though to ask your oncologist or cancer team to explain anything that seems confusing as that's the only way you can have confidence in whatever decisions you ultimately make. I wasn't opposed to radiation per se, just felt that it didn't decrease any risks I was worried about.