Hi John. my neuropathy has been a problem for about 12 years only the numb feeling from diabetes. Then when I started chemo pills 3 years ago it has got worse, it's mainly my toes. As far as my Myeloma I'm doing pretty good, when I first started Revlimid I had loose stools and short of breath which I landed in hospital. Breathing treatments helped a lot and I don;t have that anymore. I'm doing good on the Revlimid thats all I take now for over a year for cancer. As far as the toes I just hope the whole foot never goes numb! Thanks for asking about the MM!! Take care and thanks again!!