Hi @rnagle0322 Do you have a hotel in mind? It’s perfectly fine to call the hotel directly and schedule your room for however long you need to stay.
Have you gone online to look for lodging near the clinic?
Which Mayo campus will you be visiting?

Yes, call hotel directly and ask about Mayo discount. Many hotels offer and the discount may not be available online.
If in Rochester and not staying downtown, ask if hotel provides shuttle.
Laurie

I stay at Econolodge on S Broadway in Rochester. I call the hotel directly to make reservations. I have been staying there annually since 2015. Wonderful continental breakfast, exercise room, next door to Perkins, friendly staff, free shuttle to the clinic, reasonable pricing (Mayo Clinic rate), clean rooms with bare floors. I absolutely love that they have no carpet in the rooms. Makes for a much cleaner room. No worries if you need to change your reservation due to scheduling at Mayo. Have to leave early? No problem. If you need to extend and they are at full capacity you are put on a wait list. When I was there this past June they were not close to running at full capacity as they were prior to Covid.