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Treating Osteoporosis: What works for you?

Osteoporosis & Bone Health | Last Active: Sep 2 10:11am | Replies (1085)

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@notmoff

The Calton described horrors are mostly in the other drugs. Glad to hear you find Tymlos helpful.
But since you asked . . .
This excerpt (please excuse my typos) is from the Calton 2019 "Build Your Bones" book, page 34-5 that ..."Abaloparatide is a newcomer to the osteoporosis drug market, approved by the FDA in 2017. It's a small tweak on teriparatide that the pharmaceutical companies are hoping brings them a big monetary reward. Because of their chemical similarities, these two drugs have similar adverse effects. However, there are some pluses and minuses to choosing abaloparatide vs teriparatide. First, and this is a plus, our odds of getting hypercalcemia are less. On the mnus side, although the initial increases in the bone formation marker were similar for abaloparatide and teriparatide within the first month, by month three, bone formation began to decrease in the abaloparatide group compared with the teriparatide group. Basically, it's not as good at building bone. Both cause plausible increases in cortisol and calcium levels, as well as decreases in cognition and magnesium levels. Here again, the main issue is cancer. . .

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Replies to "The Calton described horrors are mostly in the other drugs. Glad to hear you find Tymlos..."

There has not been a single case of bone cancer among people using Forteo (or Tymlos). The black box warning has been taken off Forteo and it can now be used for more than 2 years. This will most likely also happen for Tymlos but since it is new, it takes longer.

I have had breast cancer (2015) with risk of metastasis to bones but feel perfectly safe taking Tymlos.

These scare tactics are affecting people's health. There are certainly side effects and for some, possible health effects, but they need to be conveyed responsibly.

I would like to see the info on bone formation with Tymlos versus Forteo in the actual text on this, and any graphs.