11 years out on my heart transplant. take 1.5mg of tacromilus per day. over the years it has been lowered but stable for 3 years. I sleep ok, have occasional tremors in the hands, and suffer from low GFR (54) and high creatinine (1.4). take 400mg a day of magnesium which works well for me. My problems with high levels of tacromilus were nausea and headaches. I am told I am probably one of the lucky ones with very mild side effects from all the drugs, and actually have >25000 antibodies on a labcorp test against covid. My keys to success are diet, exercise, and a obsessive approach to making sure I get enough fluids and electrolytes each and every day.