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What did you experience when cutting down Tacrolimus?

Transplants | Last Active: Feb 3 4:45pm | Replies (47)
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@scottij

Tacrolimus causes magnesium deficiency. If you are deficient in magnesium your nerves don't "fire" very well and hence the cramping; most often in your extremities -- hands and feet. The supplements replace the lost magnesium and hence relieve cramping. Magnesium is also often used to help people sleep as it helps relax the muscles (a relaxed muscle does not cramp, right?).
Best always,
s!

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Replies to "Tacrolimus causes magnesium deficiency. If you are deficient in magnesium your nerves don't "fire" very well..."
echo2022 | @echo2022 | Dec 31, 2022

I got some magnesium supplements, but I haven't taken them. I'll try it. Thank you very much.

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nlad4 | @nlad4 | Feb 2 12:10am

In a sleepless night I stumbled across this board. My transplant was 12/2021 I have had cramping issues my whole life. It became even worse PT. I’ve done a lot of looking and this is the first time I have heard magnesium.

Thank you for sharing!

I’m on 2mg Morning and Night working down to hopefully not needing it. Cautiously optimistic.

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