I am 9 months post transplant. I take 2mg of tac in the morning and 2 mg in the evening. I also take 150 mg of Imuran in the evening. I used to take tac and Myfortic, but I had horrible headaches and diarrhea from the Myfortic. I have had sleep issues since my transplant and some tremors. Hopefully as I go along my meds can be reduced further. I remember in the beginning I was on a boat-load of medications, so it is better.