Collen…. so far so good. I was comatose for 4 days before my kids found me in a puddle of blood, I had bleed out from my menstrual period. The doctors did plasma exchange….for two weeks and barely a response. Finaly they tried Rituxan alongwith a high dosage of predisone. But, yes….the Rituxan treatments we saw an increase of platlets which helped the Adams13 to rise out of the negative. It was a miracle….. at the start I had no platelets, Adams13 was non exrxistent, no blood, had to get several blood transfusions, along with 20 or more bags of plasma and this is what I was told from my hematologist after waking up