I have pudendal nerve damage. The damage started in my feet and spread up the backs of my legs to my glutes. It caused sexual distinction as well, plus slow bladder. I take Lyrica. All this was caused from lupus. Winsantor just sent me an email about the third Pirenzepine (WST-057) trial enrollment. I was shocked. I hope I get accepted because this cream reverses pn in people the first and second trials. It has a good safety profile.