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Transplant: New Covid booster and Evusheld

Transplants | Last Active: Sep 18, 2022 | Replies (26)

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@hello1234

Hi @contentandwell 😊
Thanks so much for your detailed response. I think you have an excellent vaccine plan! After all my covid vaccines and boosters, I tested for antibodies and had ZERO so it was recommended that I proceed with Evusheld which I did.
Recently, just a couple of weeks ago, I was diagnosed with the BK virus. The treatment for BK virus is reduction in immune suppression meds in hope that my immune system will kick in enough to handle it. BK is scary for a kidney transplant patient because it can cause rejection.
In the meantime, it's now time for my next Evusheld. I am also thinking that the reduction of immune suppression may allow me to achieve some antibodies using the new covid booster. I heard on one of the John Hopkins webinars that the vaccine is a broader protection than Evusheld if your body builds antibodies from it, so it may be worthwhile trying. I will also get the flu shot and shingles shot.
Of course, with my BK virus I am not sure what the best timing is with all of these vaccines because my top concern is the resolution of the virus and preventing rejection. I don't want to distract my immune system from job one! (Not sure if that's something real or not).
I am so happy to hear that your system successfully responded to the covid vaccine and boosters! What immune suppression meds and dosages are you on for maintenance? Also, how did you feel after your first Shingrix vaccine? (I have heard sometimes people don't feel well after the shingles vaccine)?
Thanks again JK for jumping in and letting me know your vaccine and booster plan. It's very helpful and appreciated!

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Replies to "Hi @contentandwell 😊 Thanks so much for your detailed response. I think you have an excellent..."

@hello1234
I really wonder if despite being extraordinarily careful I could have had an asymptomatic case of Covid since I had fairly high antibodies. I don't know the actual number but apparently, it was pretty good. I am on 2.5mg of sirolimus. had been on tacrolimus but it was causing my creatinine number to be high. They had me drinking 80-100 ounces of water a day to offset that. It helped but not enough so they changed me to sirolimus. I was also on a very small dose of prednisone until sometime in the last year. I really wanted to get off of it so they finally allowed me to try not taking it and my numbers stayed the same so they took me off of it. PHEW!

I had no reaction after my first Shingrix vaccine. Maybe a sore arm but that's to be expected. I have heard people are more apt to react after the second shot so I am timing it so that I have nothing that needs to be done for a couple of days after getting it.
JK