Anyone taken Evenity (romosozumab) for Osteoporosis?

Posted by arlene7 @arlene7, May 27, 2020

Has anyone taken Evenity? I understand it’s only been on the market for a little over a year. I’m hoping it will help with my severe osteoporosis. Any information is helpful.

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@dchfl

I received my last Evenity shot (#12) in July and just had a DEXA done. Here are the before and after T-score results:

Spine before: -4.6
Spine after: -3.4
Femoral neck before: -2.9
Femoral neck after: -2.5
Total hip before: -2.3
Total hip after: -1.7

Very happy to see improvement. I was lucky in that I did not have any side effects from the Evenity. Will be meeting with my Rheumatologist next week to discuss what medication to take next.

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Very encouraging!
I had my first Evenity injection mid-August. Opted for the back of each arm, only side effect was tenderness for a day and a half.

Can I get some input on preventative measures taken for replacement of crown? Dentist indicated that I’m at the point where it won’t be considered too invasive, but cautioned that if I prolong beyond six months it could likely be more invasive. He indicated that he would defer to my endocrinologist with regard to what medication (amoxicillin) should/could be taken in advance of procedure. Thank you in advance for your input.

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@amli65

I’m new to this site. My doctor wanted to start me on Evenity for my osteoporosis. My health insurance denied approval for it. However I am now on original Medicare part A & part B. As I understand it part B covers Evenity. I know it’s expensive. I’m trying to find out what it’s going to cost a month as I am retired I will have to budget for it. Is anyone on Medicare taking it with no other coverage. What is the cost ? Thanks

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My Anthem BS/BC covered all but a monthly $391 co-pay, plus the ENT visit. This put a really big dent in my budget over 12 months, but was worth it, since I got a great improvement in my scores as a result.

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@ceciliamarypatriciafrancis

My Anthem BS/BC covered all but a monthly $391 co-pay, plus the ENT visit. This put a really big dent in my budget over 12 months, but was worth it, since I got a great improvement in my scores as a result.

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Really, I have federal basic BC/BS ,which I think is part of Anthem, and they denied approval for Evenity. The doctor is putting it through Medicare which is primary to BC/BS (secondary), I trying to find out how much Medicare is going to cover. I’m glad to hear you are doing well with Evenity, I am worried about side effects. Thank you for the info.

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@ceciliamarypatriciafrancis

My Anthem BS/BC covered all but a monthly $391 co-pay, plus the ENT visit. This put a really big dent in my budget over 12 months, but was worth it, since I got a great improvement in my scores as a result.

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Sorry Evenity was not completely covered but so encouraging that you got good results taking it. Thanks so much for sharing your experience.

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@betsee

Very encouraging!
I had my first Evenity injection mid-August. Opted for the back of each arm, only side effect was tenderness for a day and a half.

Can I get some input on preventative measures taken for replacement of crown? Dentist indicated that I’m at the point where it won’t be considered too invasive, but cautioned that if I prolong beyond six months it could likely be more invasive. He indicated that he would defer to my endocrinologist with regard to what medication (amoxicillin) should/could be taken in advance of procedure. Thank you in advance for your input.

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I asked specifically about dental work and Evenity and was told that if I need something done (at the age of 68 I have a wisdom tooth coming in, darnit!) to go ahead and do it while I'm on Evenity. She said the indications of jaw osteonecrosis is very low with Evenity, because the anti-resorption properties aren't as high with it as with most other drugs. The main thrust of Evenity is bone-building, which is why in most cases, we'll need to follow up with another medication to protect the gains. She also said the only case she personally had seen with jaw osteonecrosis was someone that had to have 4 teeth removed and was on another drug. I don't recall which it was, but it wasn't Evenity.
Be sure and ask your health care provider for yourself, but thought I'd relate what I was told by my health care pro.
good luck!

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Thank you for providing the guidance you received from your healthcare professional. I’ll follow-up with my endocrinologist for advise on pre-procedure medication recommendations.

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@willow10

I asked specifically about dental work and Evenity and was told that if I need something done (at the age of 68 I have a wisdom tooth coming in, darnit!) to go ahead and do it while I'm on Evenity. She said the indications of jaw osteonecrosis is very low with Evenity, because the anti-resorption properties aren't as high with it as with most other drugs. The main thrust of Evenity is bone-building, which is why in most cases, we'll need to follow up with another medication to protect the gains. She also said the only case she personally had seen with jaw osteonecrosis was someone that had to have 4 teeth removed and was on another drug. I don't recall which it was, but it wasn't Evenity.
Be sure and ask your health care provider for yourself, but thought I'd relate what I was told by my health care pro.
good luck!

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This kind of matches with what my dentist (who is a prosthodontist) told me when I was considering taking drugs for osteopenia and alarmed about the osteonecrosis risk of Prolia and the bisphosphonates.

One thing to keep in mind is that there is 'natural' bone loss from aging that also affects the dental arch. So one needs to monitor that and do whatever bone retention efforts help bone health in general but bone loss isn't necessarily an early sign of osteonecrosis.

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@willow10

I asked specifically about dental work and Evenity and was told that if I need something done (at the age of 68 I have a wisdom tooth coming in, darnit!) to go ahead and do it while I'm on Evenity. She said the indications of jaw osteonecrosis is very low with Evenity, because the anti-resorption properties aren't as high with it as with most other drugs. The main thrust of Evenity is bone-building, which is why in most cases, we'll need to follow up with another medication to protect the gains. She also said the only case she personally had seen with jaw osteonecrosis was someone that had to have 4 teeth removed and was on another drug. I don't recall which it was, but it wasn't Evenity.
Be sure and ask your health care provider for yourself, but thought I'd relate what I was told by my health care pro.
good luck!

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That is very interesting. I called Amgen, who makes Evenity, and was told not to have any oral surgery while taking it. There is also a warning about it in the literature on Evenity.

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@bruceandruth1970

That is very interesting. I called Amgen, who makes Evenity, and was told not to have any oral surgery while taking it. There is also a warning about it in the literature on Evenity.

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thanks for checking, that's not too reassuring. IIRC, there was a post from someone who said that they were told to go off their osteoporosis med for 6 weeks, have the surgery then wait another 6 weeks for their next set of shots. I think it was Evenity, because it would be easier to pause than some of the others, but I don't remember what thread it was in. I guess we all have to discuss with our health care providers, do our own research and make the most informed choice we can. At this point, I'm not sure there is a good alternative to any of these drugs should one need oral surgery.

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Thanks for your reply. It is just so confusing when we receive different answers about these drugs. I will probably stay off Evenity for a longer period of time because I’m having an implant.

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