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Hemochromatosis & AAT

Blood Cancers & Disorders | Last Active: Sep 10, 2022 | Replies (5)

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@colleenyoung

@lclark918, Alpha-1-antitrypsin (AAT) is a protein produced in the liver that protects the body's tissues from being damaged by infection-fighting agents released by its immune system. In alpha-1 antitrypsin deficiency, the body’s normal production of AAT is reduced.

Your report states "AAT variants are genetically determined and can be associated with lung and liver injury. ... AT phenotype analysis is suggested." This means that the lab suggests that you get tested further for alpha-1-antitrypsin because it can lead to lung issues. If you have the AAT variant, it may be inherited and passed on to children, if you have any.

Definitely discuss this with your doctor at your next appointmen.

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Replies to "@lclark918, Alpha-1-antitrypsin (AAT) is a protein produced in the liver that protects the body's tissues from..."

@colleenyoung thank you for responding, I will definitely discuss this result along with other blood test to see if my declining kidney function, monoclonal protein and the hemochromatosis some how correlate. Thank you for some insight as I’m having to wait to see my doctor, and the wait can always seem like forever.