Here's the protocol my ophthalmologist put me on. I had severe dry eyes. Use the Bruders eye mask four times a day for 5-10 mins at a time for at least two weeks. After each eye mask use, use the ocusoft plus eye wipes afterwards. Then use systane ultra preservative free drops at least for times per day. These products are all available on amazon. As you improve, usually after two weeks, you can decrease how often you use the Bruder eye mask. I only need to use it once per day now with the eye wipes but I still do the drops four times a day. This regimen has helped me tremendously! My eyes are doing great per my ophthalmologist and I no longer have any symptoms.