Welcome @marinella
I'm tagging fellow members @roxanablue @blt054 @modens @pepin31219, who have experience with cryoglobulinemia and may be able to provide more insight for you.
In the meantime, you might be interested in these related discussions:
- Cryoglobulinemia not caused by hepatitis or lymphoma? https://connect.mayoclinic.org/discussion/cryoglobulinemia-not-caused-by-hepatitis-or-lymphoma/
- Cryoglobulinemia Vasculitis Question https://connect.mayoclinic.org/discussion/cryoglobulinemia-vadculitis/

Is Cryoglobulinemia a new diagnosis for you? What symptoms are you dealing with?