About 3 years ago my wife, now 81, was suffering from depression & anxiety to a degree I was fearful she would end life. A neighbor suggested CBD tincture and our doctor said that while he could not prescribe them, they would not hurt her. I read https://qualitylivingusa.com to become educated first so I began low (the dose recommended on the bottle) and increased slow as recommended. It is called "titrating up." That site endorses products it has tested. When you get to the dosage where the symptoms go away, stay on that daily. It took only 3 days for my wife to regain her positive outlook. I was dumbfounded! It has taken me a while longer to get to the dosage to significantly reduce the arthritic pain in my shoulder but it is working. I use a pain cream topical to reduce the pain in my thumb joints.