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I'm taking trazodone for sleep, but having GI side effects

Sleep Health | Last Active: Aug 18, 2022 | Replies (13)
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@linh

I too have hypothyroidism, am on synthroid and have had acceptable Tsh levels. I experienced pronounced constipation after starting the selective serotonin reuptake inhibitor (SSRI), sertraline. I see that trazodone is classified as a serotonin antagonist and reuptake inhibitor. Although not the same drug I can't help but notice the reuptake inhibitor similarities. If anyone's G.I. system is too active this works like a charm!

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Replies to "I too have hypothyroidism, am on synthroid and have had acceptable Tsh levels. I experienced pronounced..."
tugcteek | @tugcteek | Aug 15, 2022

Thanks for your response. More to think about. As with any medication it's always a challenge to find the balance between the help it provides and side effects. At some point I would like to imagine not taking this med but haven't started down that road yet. Have had limited success with halving the dosage. From my understanding trazodone is not physically addictive but my experience has been there is a psychological dependence. Would be interested in hearing more about this. Thanks

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