Hi Colleen. I wonder if Dr. Poland could provide more information on risks of covid to cancer patients, especially lung cancer patients. If one is fully vaccinated, boosted and not on medication, how much should one restrict activities? How much is Paxlovid helping such high-risk patients? Obviously, people with lung cancer have compromised lungs, but without quantifiable information, it is impossible to weigh the risk, and decide if something is worth the risk. For example, should one take that special trip to Europe if it means not having access to the anti-viral Paxlovid in case of need? Thanks.