No, fortunately I was lucky with that - my only complaint was the $90 monthly co-pay. In retrospect it's a little scary having to take something with 8 or more ounces of water before eating and staying vertical for 30 minutes...why? I'm very obedient with doctors since I live in Yale land and have excellent providers. I've mentioned before that I recently finished a year-long expensive course of Evenity with great success, so I do what I'm told for the most part. I have had to go back on Actonel again, though to keep up the good work, so it never seems to end.