Hi @jackiez 😊
You are soooo right about our balance act of the immune suppression meds. It's such a fine line between rejection and infection for us. I was on 1000mg bid Cellcept and had leukopenia, neutropenia, high liver enzymes, then I got the CMV virus. They lowered my Cellcept to 500mg bid to fight the virus. About 90 days after the reduced dosage I had a biopsy that showed no rejection so they recommended that I stay on the reduced dosage to avoid all the adverse effects. How long after the change from Tacronlimis to Sirolimus did you have your biopsy? I am so happy that they caught your cellular rejection and jumped on it with an increase of suppression! (I assume you had no symptoms so the biopsy and it's timing was excellent so they could tweak your meds). Are you scheduled for a follow up biopsy so you can be reassured that "all is well" now?