Hello @cfbauer, Welcome to Connect. Here are a few studies on the topic.

"Major AREDS/AREDS2 findings:
-- 1. Taking AREDS or AREDS2 supplements reduces the risk of progression from intermediate to advanced AMD by about 25 percent
-- 2. AREDS and AREDS2 supplements do not prevent AMD onset
-- 3. AREDS and AREDS2 supplements do not have an effect on cataract
-- 4. Omega-3 fatty acid supplements do not have an effect on cataract or AMD
-- 5. Current and former smokers should take the AREDS2 formula and avoid the AREDS formula with beta-carotene, which increases lung cancer risk"
--- Age-Related Eye Disease Studies (AREDS/AREDS2) - major findings: https://www.nei.nih.gov/research/clinical-trials/age-related-eye-disease-studies-aredsareds2/about-areds-and-areds2

-- Age-Related Eye Disease Studies (AREDS/AREDS2) - What do the AREDS studies mean for you?:
https://www.nei.nih.gov/research/clinical-trials/age-related-eye-disease-studies-aredsareds2
You might also be interested in the following discussions:
-- AREDS 2 and side effects: https://connect.mayoclinic.org/discussion/areds/
-- Areds 2 (PreserVision): Anyone experienced muscle pain?: https://connect.mayoclinic.org/discussion/areds-2-presservision-and-muscle-pain/

Have you discussed taking AREDS 2 with your eye doctor?