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Triple Negative Breast Cancer: What treatments are you having?
Breast Cancer | Last Active: Sep 6 11:41am | Replies (244)Comment receiving replies
As I understand it, with triple neg it is a matter of druggable targets and being able to truly get rid of it in the first place. This is the biggest problem that researchers I have met want to solve. I do know for positive there is literally an army of doctors and researchers working on this, and things are getting better all the time. The same is true with the her2, oncotype which is truly an aggressive form because of the way it grows. I would love to read anything that says triple neg is less likely to recur. That would really bring me joy.
How are you feeling with all of your treatments?
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The article that I posted above addresses the difference in the pattern of recurrence for triple negative compared to ER+ breast cancer.
"Many triple-negative breast cancers differ significantly from hormone-positive tumors in that they are less likely to recur late, that is, five or more years following diagnosis.
With estrogen-receptor-positive tumors, the incidence of recurrence remains steady for at least 20 years following the diagnosis, even for very small, early-stage tumors. In fact, people who have estrogen-receptor-positive early-stage breast cancer are more likely to have a recurrence after five years than in the first five years following diagnosis.
In women with hormone-positive tumors who are treated with hormonal therapy for five years after surgery and/or radiation/chemotherapy, the distant recurrence rate between year five and year 20 ranges from 14% for small, node-negative tumors (T1N0) to 47% for larger tumors that have spread to lymph nodes (T2N4-9).8
The lower incidence of late recurrence with triple-negative breast cancer wasn’t as clear until recently, as many studies only went out five years when looking at recurrence and survival.
A 2018 study, however, looked at people with triple-negative breast cancer who were disease-free five years after their diagnosis. Among this group, the 10-year recurrence-free rate was 97% and the 15-year recurrence-free rate was 95%."