← Return to Brachioradial pruritus. (severe itching on forearms and neck, no rash).

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BRP due to neuropathy of the small C fibres may respond exceptionally well to Perineural Injection Therapy. It is a neuropathic itch and subcutaneous injections with Dextrose 5% reduce neurogenic inflammation and symptoms. See more about PIT on John Lyftogt’s website. . I’ve had great success with treating the anatomical fields of the radial (and all it’s distal branches) and axillary nerves. This is anecdotal, but a low risk procedure with minimal side effects. Topical creams only mask the symtoms or modulate the pain whereas PIT treat the condition. I’m also using it for notalgia paresthetica a similar neurophatic condition.

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Replies to "BRP due to neuropathy of the small C fibres may respond exceptionally well to Perineural Injection..."

Where does one go for this injection therapy? Interesting and hopeful treatment.

John Lyftogt’s website has a list of trained physicians.

Any chance I can come to see you? I live in Northern Virginia, but travel a lot. Martin

I am not familiar with perineural injection therapy or neural prolotherapy. Doing an extensive internet search of both terms, I found that research is promising, but not yet conclusive.

This study for example shows effective results in a small group of people with carpal tunnel syndrome http://www.mayoclinicproceedings.org/article/S0025-6196(17)30406-8/abstract

Keep in mind that this therapy can be expensive. The FDA does not approve the use of these injections at this point, so it is still a cash-based procedure. Just because treatment is expensive doesn’t necessarily mean it’s the most effective treatment.

It is important to note that "The American Pain Society recommends against prolotherapy for treating low back pain, but other authorities are suspending judgment until larger, more-thorough studies have been done. Until then, talk to your doctor before deciding whether prolotherapy is right for you." https://www.mayoclinic.org/prolotherapy/expert-answers/faq-20058347

Hi Martin
I live in Canada Better to find someone closer to you and do an injection trial . They usually get significant relief right after the first treatment . If they have a significant response they are booked for injections every 1-2 weeks till their symptoms under control See Practitioners Perineural injection therapy website Dr. John Lyftogt

Hi Colleen

Here is some new promising data:
Short Term Analgesic Effects of 5% Dextrose Epidural Injections for Chronic Low Back Pain: A Randomized Controlled Trial
liza Smigel et al: Anesth Pain Med. In press(In press):e42550.

Perineural Injection Therapy in the Management of Complex Regional Pain Syndrome:Pain Medicine 2017; 0: 1–4 doi: 10.1093/pm/pnx063

Transition from Deep Regional Blocks toward Deep Nerve Hydrodissection in the Upper Body and Torso: Method Description and Results from a Retrospective Chart Review of the Analgesic Effect of 5% Dextrose Water as the Primary Hydrodissection Injectate to Enhance Safety. Hindawi BioMed Research International Volume 2017, Article ID 7920438, https://doi.org/10.1155/2017/7920438

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