I think immunotherapy is important for TNBC since it doesn’t respond to hormone treatments. I’m on that and chemo for 1/week for 12 weeks to get a complete result (no cancer detected) before surgery. I know everyone’s path is different though. I am getting my treatments at Mayo. I think their standard for a tumor size T3 not spread is AC and immunotherapy for 12 weeks. Then another combo for another 3 months for a total of 6 months before surgery. I am in I Spy 2 study too though which is a d escalation less harsh path. Get all your options, take someone with you to take notes. Ask all the questions for each treatment option. When you do a study, they have to redo biopsies and MRI’s and wait for your drugs to get selected (2 weeks in my case) so it delayed treatment start by 3 weeks which was nerve racking and not for everyone. Let me know if you have questions!!