Sounds like you are an overachiever with a 3x the-normal-size spleen. Mine was only twice its normal size! I was lucky as I never had night sweats and any temperature. I too went through a lot of changes. I started treatments in January of this year, after 'firing' my previous oncology practice that was slow to respond to phone calls, emails and even feed back on my newly discovered cancer. I was treated like one more sick person in their waiting room and everyone, including the staff looked lifeless and uncaring. I drive an hour away to a clinic that is well worth the trip, as everyone is happy, my doc is the head of the clinic, so anything she wants done to me, gets done pronto! I started working from home in January and went back to work 2 weeks ago. In February I put my little house up for sale and sold it within that week, weeks later I hit a large deer or it hit me, if I am being honest, and caused $11,000 worth of damage to my 2 year old car. I moved in March to a condo where I can manage everything better, but I do miss my vegetable, herb and flower gardens, but not the grass cutting and weeding. I turned 70 in May and lead a pretty active life (gym classes, yoga, pickle ball) and intend to keep working until the end of the year. The unknown is whether I will have to have Rituxan treatments until the end of my life and they are costly. If you want to connect to chat, I am up for it. Thanks for listening.