I've been taking nsaids (aleeve) for almost 40 years. Only issue I have had is when I don't take them. I have been on so many different "pain" killers too. I would rather take the nsaids than narcotics any day. I have had a hip replacement, 3 back surgeries, a neck surgery, many other issues due to an inherited condition called Ehlers Danlos. It's a connective tissue disorder. Pain was an everyday intense problem for me. I recently tried cbd oil gummies. They have helped me immensely. I no longer take any pain meds and my depression has subsided immensely. Doc also had me try antiinflammatory diet. I was also told and researched that pain meds after a long time of using will no longer work and can actually cause more pain which increases the use and dosage of them. Therefore it leads to an addictive state. Wishing you all the best !!