The general feeling among my medical team, my "research," well, Google...and the forums I am part of lean towards exercise as a way of mitigating the side affects. I say mitigating because in no way do I infer it eliminates. Throughout the 18 months there were times I felt like I was 90+ years old, particularly in the evening when I settled down for a glass of wine and some television watching. Getting up to grab a a refresher, snack, use the facilities or go to bed was a lot of stiffness though I wouldn't say pain.

True, I went in to the 18 months with an active exercise program. For those who do not, it may be challenging to start. Though I do think if one can get through the initial phase of exercising, there can be benefits. A body in motion,,,