Hi Chris. You sound like me with those reactions to multiple things. I have also ended up in the ER. Glad you can see the bright side: avoiding the kitchen!

I have read and been told by my doctor that Benadryl and tylenol can be taken before a Reclast infusion, along with hydration and a slower infusion. I have heard the same for Prolia (my doc doesn't want me on Prolia so his comments were only about Reclast). I would also add Pepcid, myself.