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MGUS and quite high Free Kappa Light Chain and Kappa Lambda Ratio
Blood Cancers & Disorders | Last Active: Aug 3 1:59pm | Replies (203)Comment receiving replies
Anyone with high 28.9 kappa but lamb a 24.1
I also have Undifferentiated Connective Tissue Disease . I have MGUS but no m spikes for a year . I keep reading about Kappa Myeloma , is that a disease all it's own ? My hematologist says as long as ratio is fine so am I .
Replies to "Anyone with high 28.9 kappa but lamb a 24.1 I also have Undifferentiated Connective Tissue Disease..."
My husband has 27.18 mg/L for Lambda Qnt Free Light Chains, K:L Free Light Chain Ratio of 1.49 and Kappa Qnt Free Light Chains value 40.61 mg L and is receiving intravenous Gamunex-C infusion therapy for Chronic Inflammatory Demyelinating Polyneurophy (CIDP). Does anyone else have s similar experience?
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@confusedkoala As I recall from studying my own situation, there is too much emphasis placed on just the kappa-lambda ratio. Truth is, that ratio is very important, BUT only as long as both K & L are within the target range. If EITHER slips out of range, that is a danger sign and should be investigated much farther. Or, if only the proBNP blood protein gauge is used, and not the NTproBNP, your hematologist needs a little education. And the sFLC (Bindings) is critical. oldkarl