← Return to My Experience on Evenity for Treating Osteoporosis

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@lbmorgan44

I have been on Evenity for 7 months and had few side effects. The endcrinologist is recommending Prolia when I go off Evenity. I am looking for alternatives and considering HRT (Hormone Replacement Therapy) to stop on-going bone loss. I am 76 and have had one broken bone prior to Evenity with a DEXA score of -2.67. Has anyone had any experience with HRT for bone loss after the age of 60?

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Replies to "I have been on Evenity for 7 months and had few side effects. The endcrinologist is..."

@lbmorgan44 Have you considered Reclast instead of Prolia? The same company, Amgen, makes Evenity and Prolia so it seems a lot of folks are doing that combo. But you cannot just stop Prolia, because there is a quick drop in density when you do, according to doctors I know. On the other hand, Reclast may be able to be given in a partial dose and with proper monitoring, can be stopped and then started again when needed. Again that is what my doc said. Your bone density score is not that bad- just over the line of osteoporosis. Are they sure you broke that bone because of osteoporosis?

From the Mayo Clinic (excerpted) on risks of HRT - scroll down for risks over 60.
https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/ART-20046372

What are the risks of hormone therapy?
In the largest clinical trial to date, hormone replacement therapy that consisted of an estrogen-progestin pill (Prempro) increased the risk of certain serious conditions, including:

Heart disease
Stroke
Blood clots
Breast cancer
Subsequent studies have suggested that these risks vary depending on:

Age. Women who begin hormone therapy at age 60 or older or more than 10 years from the onset of menopause are at greater risk of the above conditions. But if hormone therapy is started before the age of 60 or within 10 years of menopause, the benefits appear to outweigh the risks.
Type of hormone therapy. The risks of hormone therapy vary depending on whether estrogen is given alone or with progestin, and on the dose and type of estrogen.
Health history. Your family history and your personal medical history and risk of cancer, heart disease, stroke, blood clots, liver disease and osteoporosis are important factors in determining whether hormone replacement therapy is appropriate for you.

ps I have had hormone-driven breast cancer so cannot do HRT anyway...