ER+ Mutated no longer using Estrogen: ESR1 And PIK3CA Mutations

Hi,

Not to go back in time with my history, but when I was first diagnosed toward the end of 2019, I was considered "Low Volume". That means that the cancer didn't spread to more areas than it should have. The main areas were my left breast, 2 lymph nodes under my left armpit and the T-11 vertebrae on my back. I had sought a 2nd opinion and was put on Ibrance (targeted therapy) Lupron Injection and Letrozole (both to stop the production of Estrogen/Progesterone that was driving my cancer. In 2020, both my PET Scans were clear of any disease, but I was told to continue taking the anti-hormonal medication that my doctor recommended, so I did. Fast forward to 2021, a small tumor showed up in my left Iliac hip bone and my doctor recommend that I go back on the Ibrance, which I did. I ended up getting targeted radiation for it, which cleared it, but in the interim, a tumor showed up in my left breast, which was the same place it started. I had a biopsy and was informed that it mimicked my original diagnosis (ER/PR+ and HER2-) and I could either start a 3rd anti-hormonal treatment or opt for an Oophorectomy (removal of both ovaries and fallopian tubes. I went for the source and had them removed. The 2nd test that came back indicated I had developed an ESR1 mutation and was informed I would need to go on a Fulvestrant Injection (Anti-hormonal). When I asked my doctor whether I would develop another mutation to this treatment, should could not confirm our deny. At that point, I was at a cross road because I did not want this to develop into more mutations and all of a sudden I would not be able to control the spread. Now mind you, I had already incorporated natural supplements, herbs and CBD into my daily regiment. By doing research into Integrative Clinics and the programs they offer regarding healing the entire body and flushing it of toxins, chemicals, etc., I decided to take that route. I walked away from my conventional doctor and sought treatment with an integrative specialist that offered Ozone and IV Vitamin C therapy. The Ozone therapy treatment goes through an irradiation process of the blood, which cleanses it, and the IV-Vitamin C is extremely effective as well. I am sorry for making this response long-winded, but felt I needed to detail my journey a little bit. My take away from this is if I continued on the path of conventional treatment, these tumors will become stronger and more resistant to medication, I will not be able to stop it by my lifestyle change.

I hope this helped.

TY so much for your kind helpful reply .Those dispensaries are in Washington , not OR but there are many many here too. I just don't know how to figure dosing ,maybe its more start low and see what works for you ? Not a smoker either , and that black stuff is so sticky ( I tasted it and it stuck to my teeth ,LOL ) I had someone tell me she placed it on her feet , to draw out poisons , while doing chemo treatments . Sounds like it would be very worthwhile to have studies and research on that , but of course Big Pharma would lose $$$ , Can you tell me what the peanut butter does , cover the taste ?

Hi! I hope you do find a dispensary near you that can offer the RSO. For me, when I started, I had contacted the pharmacist at the dispensary that I go to and she walked me through everything. I told her what my diagnosis was and how I wanted something that would help shrink tumors. She was extremely helpful and knowledgeable and recommend that you start out with a 1/2 grain of rice (the size of a grain of rice) and gradually work your way up. She suggested peanut butter because of its ability to absorb the RSO into the body easier and is considered a protein. I just put a little bit on a spoon and add a drop of the RSO to it. She also suggest I take it at night approximately 1 hour before I go to sleep. I want to add that when I had found a holistic doctor who would accept me as a patient and provide me with a certification number to apply for my medical marijuana license, my doctor suggested the same thing with dosing. He stated you never want to start out with a high dose. You start out with a 1/2 grain of rice for about a week, then work your way up from there.

I hope this helps you and if you should have any other questions, please feel free to contact me.

Thank you and good luck!