@cgirl0721 It is good to see you are looking in to this, as a family member and part of your sister's support team. I know she appreciates everything you are helping her with, as she navigates this new-to-her path!

There are several different kinds of myeloma [hence the title multiple!], and treatments can vary with each type. Also, if there are additional health issues present, treatment may also be modified to take those in to account. I have added the link from Mayo Clinic for multiple myeloma for you to read. Because blood cancers are systemic, traditional surgery is not an option. An additional source for information is the International Myeloma Foundation, that link also here.

Your sister will perhaps go through periods of exhaustion, mental confusion, maybe even grief as she deals with a different daily routine. And it's okay for everyone to acknowledge that, and be gentle. Taking medications and changing your lifestyle can be exhausting. Accompany her on appointments if you can, take notes, ask questions, don't be afraid to ask for help. And, come back here to get support yourself, and ask questions!
https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/symptoms-causes/syc-20353378
https://myeloma.org
Ginger