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Metastatic Breast Cancer treatment options

Breast Cancer | Last Active: Jul 22, 2023 | Replies (73)
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@adanab

I'm kind of amazed that there is so little medical information in this Mayo chat group. But here are my questions:
1) I'd like to know if anyone has feedback on a newer protocol/drug regime as this seems that Ibrance/Letrozole was developed 3-4yrs ago. I have Stage 4 mets BC to the bones, original cancer was in 2006. Was on Ibrance/Letrozole for only 7 months before it stopped working. 2) Am now going to regime #2 - Afinitor 10 mg/Faslodex injections. Anyone want to share their experience with regime #2?

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Replies to "I'm kind of amazed that there is so little medical information in this Mayo chat group...."
pjsfla | @pjsfla | Apr 27, 2022

I had gene sequencing , which pointed to Piqray but oncologist said no , using ibrance w Faslodex shots. From all I've read , these cancer viruses can mutate and outrun the treatments , so there are many to try when that occurs .I'm MBC stg 4 , was on arimidex which failed also , at 4+ yrs . Best Regards, please keep posting . Good Luck with this . PJSFLA

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leeann66 | @leeann66 | Apr 28, 2022

Hello, I am also stage 4 Mets to bones. Was on Kisqali and Arimidex for 18 months then it stopped. I switched to Afinitor and Exemastane but has severe reaction, rash and difficulty breathing so that was stopped after 1 month and am now started second round or Xeloda, oral chemo. So far so good! Hope they find the right mix for you, thanks fully for us there are several options!

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Colleen Young, Connect Director | @colleenyoung | Apr 29, 2022

Hi @adanab, are looking to connect with medical professionals?
Mayo Clinic Connect is an online community, hosted by Mayo Clinic, for patients to connect with other patients, share experiences, tips, and to get and give support.

You might be interested in these discussions related to your questions:
- Ibrance and Letrozole: Newly Diagnosed Treatment https://connect.mayoclinic.org/discussion/ibrance-and-letrozole-newly-diagnosed-treatment/
- Anyone have experience with Afinitor + aromatase inhibitor? https://connect.mayoclinic.org/discussion/afinitor-everolimus/
- Abemaciclib and Falsodex Treatment https://connect.mayoclinic.org/discussion/abemaciclib-and-falsodex-treatment/

@mhsosa @pampurr @sharonyb4000 @ja5747 @thielmann1 @trivia @nikki727 may be able to share more about treatmentwith everolimus (Afinitor) and fulvestrant (Faslodex).

When do you start the new regimen, @adanab?

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