I wish I had avoided taking Prolia. I decided to go off of it after 3 years and went back on Fosamx. Within the first 6 weeks of stopping Prolia I fractured 3 vertebrates, t8, t12, and L1., While taking Fosamax. I am now back on Prolia, but am worried as to what will happen if I have to go off of it after 7-10 years. I’d try other things before Prolia and pay attention to side affects listed.