Yes, heart issues can cause shortness of breath. It depends on the type of murmur involved. Some are completely harmless - then again, as we get older - things can change. There is something to the anxiety thing - and would not dismiss this. However - I will throw this out there…….DECONDITIONING can cause shortness of breath - decreased levels of activity over a period of time (such as what has occurred with many during Covid) - can take a real toll on the body - and lead to shortness of breath. Just an fyi - if you are using a statin medication for cholesterol issues - it can help with non-alcoholic fatty liver. Allergies can also trigger shortness of breath…….Just some things to ponder……I hope you and your doctors can unravel this. FYI - GERD can over time, change the way that we breathe - and we don’t realize it. Silent reflux can do the same thing. Read up on dysfunctional breathing habits……there is a lot to discover about this……There are exercises you can do, to correct any dysfunctional breathing…….that may relieve your shortness of breath. Keep us posted! So glad you are contributing here!