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Side effects of Pristiq

Depression & Anxiety | Last Active: 6 hours ago | Replies (410)
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@jeanmnyc

Hi, I have been on Pristiq-generic for about 2.5 years, now on 25 mg. I have actually gained some wt. No appetite, increased constipation, sweating, insomnia. Apathy, no sex drive, on and off anxiety and agitation, terrible sweating. I hate this stuff and I thought Effexor was bad.. I want to get off of it. Also, it seems to make me more impulsive and irresponsible. Any suggestions?

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Replies to "Hi, I have been on Pristiq-generic for about 2.5 years, now on 25 mg. I have..."
Lisa Lucier | @lisalucier | Oct 2, 2018

Hi, @jeanmnyc - welcome to Mayo Clinic Connect. I merged your post with this one, as you mentioned wanting to get off of desvenlafaxine (Pristiq), and members in this thread have been discussing just that topic.

Here is an article with some general Mayo Clinic information on antidepressant withdrawal you may find useful: https://www.mayoclinic.org/diseases-conditions/depression/expert-answers/antidepressant-withdrawal/faq-20058133.

I'd also like you to meet @casey0603 @netty @nonnivee @losangeles90027 @bonny @missymooha and others from this discussion who may have input on some of the potential side effects you've experienced on this medication and how they worked with their physicians to taper off desvenlafaxine (Pristiq). @gailb may also have some thoughts for you.

How has your depression been on this medication?

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