I have been off Pristiq for 9 days due to miscommunication between my pharmacy and my doctors office. I feel like I'm going to go crazy with anxiousness, and for the first time my blood pressure has gone from the normal 110/80 which it ALWAYS is, and as of right now is 168/115, and my pulse, resting, is 140. Between this and the feeling that my head is going to explode, I know this is really bad. I just got it refilled today, and took it in the parking lot of the pharmacy. I know that for most people, my blood pressure seems like it isn't high at all, but I am relatively healthy, other than the MS and depression, and work out when I can, my weight is fine for my height (5'8, 131 lbs) and my blood pressure and pulse are usually not an issue. At what point does the blood pressure become dangerous enough for someone without blood pressure issues that I need to address it immediately? I'm assuming it's the Pristiq withdrawl, but if it isn't, I'm in trouble. My head is killing me. I never ever fuss to anyone about my health, good, bad or otherwise, but right now, I'm feeling really strange and again, anxious. Anxious doesn't even seem strong enough to cover it. More like Hysterically on Edge and feeling like I'm about to be killed at any moment. That would be closer to describing the feeling. This is horrible.