← Return to JAK2 Mutation - Effects and Questions
DiscussionJAK2 Mutation - Effects and Questions
Blood Cancers & Disorders | Last Active: Jun 19 5:59am | Replies (303)Comment receiving replies
Replies to "I have been living with high platelets (500-680 range) since 2016. In 2017 I had a..."
My husband was diagnosed at 69, a year ago, with Primary Myelofibrosis including Jak2 mutation. A bone marrow biopsy and DNA testing confirmed this. We tried hydroxyurea but that did not shrink his spleen (as the spleen takes over the production of RBC since the bone marrow is unable to do this efficiently). Currently on Jakafi for the last 4 months, minimal side effects. We are facing a bone marrow transplant in the near future. If the spleen has not reduced in size, it will be removed and then we will proceed with the bone marrow transplant. A scary ride for sure, but it's the only cure.
Hi Cynthia, welcome. How did your appointment go today?