Plasmapheresis for brain fog in Long COVID

Posted by joelsg @joelsg, Mar 21, 2022

My 37 yr old son with Long COVID has been suffering from incapacitating brain fog for more than a year. He has tried multiple medications and rehabilitation treatments without improvement. I have found some information online that suggests plasmapheresis may be helpful and is a pretty low risk procedure. Has anyone had or know someone who has had plasmapheresis for the brain symptoms of Long COVID?

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Hi @joelsg,, the only evidence-based information that a Google Scholar search revealed referred to the potential benefits of therapeutic plasmapheresis as adjunctive treatment in critically ill COVID-19 patients.

The conclusion of this study states "The main factor in the success of plasmapheresis is to start in the early stages of inflammation, in which there is a very high concentration of inflammatory cytokines."
- Potential of therapeutic plasmapheresis in treatment of COVID-19 patients: Immunopathogenesis and coagulopathy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605792/

I didn't find anything specific to brain fog or the using plasmapheresis to aid in the recovery from long haul COVID symptoms. Did you?

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Yes I found 1 reference . See attached

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