Thanks for your reply. It gives me some insight into the fatigue that has resumed, although the pain has not. The pain levels are at 0 right now. I do have other side effects from the Prednisone. My neurologist is very difficult to get hold of, so it's been a "common sense" approach to the weaning. So down 2.5 next week. Right now I'm on 15mg. I do know there are others whose cortisol levels have leveled out since weaning off the Prednisone. Looking forward to getting some of the old "umph" back. Take care.