I started with my first Prolia injection in 2018 and just had my 8th injection last week. I am 67. I have improvement in both hip and spine (more in the spine). In my past comments I have said that I thought the Prolia made my irritable bowel and my arthritis worse but I don't know if the arthritis would have become worse anyway. And maybe or maybe not for the IBS-C. In any event, still on it. No fractures so far and wish to keep it that way.
Just know that once you start Prolia you cannot stop without
going to another drug ("relay" drug). Stopping Prolia cold turkey may lead to compression fractured. Recent research says you can stay on Prolia for 10 years. Very easy getting the injection every six months.