1. < Neuropathy

B-6 vitamin danger!

Posted by Lynsorensen @lynsorensen, Dec 11, 2017

With the assistance of a neurologist at Mayo Clinic, I have almost completely eliminated the uncontrolled muscle spasms now. First and foremost: beware of taking multi-vitamin capsules that have B6 listed. B-6 overdosage (which is contained in every multivitamin I found in stores and on the internet) can cause loss of muscle control and spasms in some people. So can gluten found in many foods so now I am also gluten free. I now work out with a personal trainer 3 days a week and do water aerobics another 2 days. Got off gabapentin and also clonazepam. Using CBD oil capsules each morning (no more opioids or chemicals) and using a CBD topical ointment to rub on my leg muscles each night. He says I don't need him anymore! And I don't. No more shaking or muscle cramps or pain. Still a little numbness but that is receding also.

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Hank | @jesfactsmon | Feb 3, 2021
In reply to @chuckfrasher "I take pyridoxal-5-phosphate which is very effective at preventing the damage from AGEs (Advanced Glycation End..." + (show)
@chuckfrasher

I take pyridoxal-5-phosphate which is very effective at preventing the damage from AGEs (Advanced Glycation End Products). I get 37.5 mg twice per day in Life Extension’s Two Per Day supplement. I take one with my early meal and one with the evening meal. I also take a 100 mg cap of pyridoxamine-5-phosphate in between these two meals. This is within the safety range. I take this along with carnosine, alpha-lipoic-acid, and Benfotiamine to prevent AGEs and I also eat a diet low in AGEs. Diabetes is accelerated aging as a result of the excess glycation of proteins and lipids so it’s best, in my opinion, to have a safe and effective approach to preventing the damage caused by diabetes. Here is a very simple article about eating a diet low in AGEs. http://www.diabetesforecast.org/2014/11-nov/foods-high-in-ages.html

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@chuckfrasher
Thanks for the article. I mentioned to you previously that we take L Carnosine to help combat AGE's. What I did not know of was the benefit of taking pyridoxal-5-phosphate. I took my wife off of the B-complex supplement she was taking because its B6 component was sourced from both pyridoxal-5-phosphate AND pyridoxine. I think I remember having an issue with the pyridoxine only. I had read that pyridoxine can be harmful for PN sufferers. I think I remember wishing it had only stated the source as being exclusively pyridoxal-5-phosphate. Can you please reference the link to the Life Extension product you take? I'd like to take a look at that. Was it a B-complex? Thanks, Hank

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Mentor
John, Volunteer Mentor | @johnbishop | Feb 3, 2021
In reply to @drb02r "Who was your Doctor at Mayo?" + (show)
@drb02r

Who was your Doctor at Mayo?

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@drb02r I'm not sure who your question is for so will tell you who I had back in 2016. My Mayo Clinic Rochester neurologist was Dr. Nathan Young who I would highly recommend. Very good neurologist but an exceptionally good people person which is one of the qualities I really like in a doctor. Fortunately for me, I haven't met many at Mayo that aren't good listeners to their patients (my number one qualifier).

If you want to ask a specific member, just add their @membername to your post to direct your question to that member.

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channelcat33 | @channelcat33 | Apr 24, 2021

My B6 blood test came back at 131 which is extreme toxicity, and I have hypothyroid. Does anyone know what works to remove B6 from the body fast besides anti inflammatory foods? I'm a female and I've lost my hair.

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2 replies
athenalee | @athenalee | Apr 25, 2021
In reply to @channelcat33 "My B6 blood test came back at 131 which is extreme toxicity, and I have hypothyroid...." + (show)
@channelcat33

My B6 blood test came back at 131 which is extreme toxicity, and I have hypothyroid. Does anyone know what works to remove B6 from the body fast besides anti inflammatory foods? I'm a female and I've lost my hair.

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Lots and lots of water. It’s a water soluble vitamin, so flushed out with water. You might also try goldenseal.

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Mentor
John, Volunteer Mentor | @johnbishop | Apr 25, 2021
In reply to @channelcat33 "My B6 blood test came back at 131 which is extreme toxicity, and I have hypothyroid...." + (show)
@channelcat33

My B6 blood test came back at 131 which is extreme toxicity, and I have hypothyroid. Does anyone know what works to remove B6 from the body fast besides anti inflammatory foods? I'm a female and I've lost my hair.

Jump to this post

Hello @channelcat33 - I would like to add my welcome to Connect along with @athenalee and other members. If you are taking any daily vitamins you might want to check them as a source of too much B6. You can find more information on B6 here:

Vitamin B6 - Health Professional Fact Sheet: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

Here's some more information - "Jan 15, 2021 — Can vitamin B6 be harmful? People almost never get too much vitamin B6 from food or beverages. But taking high levels of vitamin B6 from supplements for a year or longer can cause severe nerve damage, leading people to lose control of their bodily movements." -- Vitamin B6 - Consumer - Office of Dietary Supplements - NIH: https://ods.od.nih.gov/factsheets/VitaminB6-Consumer/

Did your doctor have any suggestions to help you lower the B6 levels?

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1 reply
12cmgc | @12cmgc | Feb 22, 2022
In reply to @johnbishop "Hello @channelcat33 - I would like to add my welcome to Connect along with @athenalee and..." + (show)
@johnbishop

Hello @channelcat33 - I would like to add my welcome to Connect along with @athenalee and other members. If you are taking any daily vitamins you might want to check them as a source of too much B6. You can find more information on B6 here:

Vitamin B6 - Health Professional Fact Sheet: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

Here's some more information - "Jan 15, 2021 — Can vitamin B6 be harmful? People almost never get too much vitamin B6 from food or beverages. But taking high levels of vitamin B6 from supplements for a year or longer can cause severe nerve damage, leading people to lose control of their bodily movements." -- Vitamin B6 - Consumer - Office of Dietary Supplements - NIH: https://ods.od.nih.gov/factsheets/VitaminB6-Consumer/

Did your doctor have any suggestions to help you lower the B6 levels?

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Having had a B6 level of 505 and now back to normal; does genetics play a role in why some people retain more of it rather than eliminating it?

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1 reply
Mentor
John, Volunteer Mentor | @johnbishop | Feb 22, 2022
In reply to @12cmgc "Having had a B6 level of 505 and now back to normal; does genetics play a..." + (show)
@12cmgc

Having had a B6 level of 505 and now back to normal; does genetics play a role in why some people retain more of it rather than eliminating it?

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Welcome @12cmgc, You ask a good question. Here's what I've found out -- "Is vitamin B6 deficiency genetic?
In addition, vitamin B6 deficiency can result from malabsorption syndromes, such as celiac disease, Crohn's disease, and ulcerative colitis. Certain genetic diseases, such as homocystinuria, can also cause vitamin B6 deficiency [2]. Some medications, such as antiepileptic drugs, can lead to deficiency over time." --- Vitamin B6 - Health Professional Fact Sheet: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

Here's another reference that I think reads a little easier. - How Genes Influence Your Vitamin B6 Requirements: https://www.xcode.life/genes-and-nutrition/genes-vitamin-b6-requirements/

Have you been diagnosed with any condition related to B6 levels?

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1 reply
12cmgc | @12cmgc | Feb 22, 2022
In reply to @johnbishop "Welcome @12cmgc, You ask a good question. Here's what I've found out -- "Is vitamin B6..." + (show)
@johnbishop

Welcome @12cmgc, You ask a good question. Here's what I've found out -- "Is vitamin B6 deficiency genetic?
In addition, vitamin B6 deficiency can result from malabsorption syndromes, such as celiac disease, Crohn's disease, and ulcerative colitis. Certain genetic diseases, such as homocystinuria, can also cause vitamin B6 deficiency [2]. Some medications, such as antiepileptic drugs, can lead to deficiency over time." --- Vitamin B6 - Health Professional Fact Sheet: https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

Here's another reference that I think reads a little easier. - How Genes Influence Your Vitamin B6 Requirements: https://www.xcode.life/genes-and-nutrition/genes-vitamin-b6-requirements/

Have you been diagnosed with any condition related to B6 levels?

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As mentioned B6 level was 1000% over in the past but now normal. I have now moved on to Parkinsons....... whether B6 caused it after the excess B6 not being diagnosed for almost three years, or it may have been in the background. Thanks for the information.

REPLY
1 reply
12cmgc | @12cmgc | Feb 22, 2022
In reply to @12cmgc "As mentioned B6 level was 1000% over in the past but now normal. I have now..." + (show)
@12cmgc

As mentioned B6 level was 1000% over in the past but now normal. I have now moved on to Parkinsons....... whether B6 caused it after the excess B6 not being diagnosed for almost three years, or it may have been in the background. Thanks for the information.

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One final question..... is there something one can take to reduce abnormally high B6 levels? I have a colleague taking no vitamins and on a minimal diet that is in the 180 range and slowly increasing.

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