Thanks for your info—realize your a patient like me—thought site would be more up to date on info—maybe giving research things and offering “clinical trials” and stuff like that—have actually talked to Stanley Kim myself and he had a “zoom” with Peripheral Neuropathy Success Stories” on 1/13–If drug works it “could” be for most any neuropathy(testing now is diabetic) but cause would have to be “fixed”—which is why “I go nuts” when people use the word “idiopathic”—there’s a “cause” for everyone! Find it! Find a doctor who won’t stop looking! It WON’T stop on it’s own! I’m more than a fighter(it’s getting old)—there has to be “a way out of this” and I’ll find it—you may want to join PNSS—more up to date info there and “zoom” calls with “experts” every 2 weeks
So instead of just pain drugs, there are medications that are in human trials for nerve regrowth and (maybe) more to come.
Winsantor, Regenancy, Disarm all believe neuropathy is caused mitochondria dysfunction in nerves. There are different processes driving it (chemotherapy, HIV, diabetes and even some types of CMT) but they all seem to cause nerve destruction in a similar way.
Winsantor's drug attenuates a constraint that peripheral nerves operate under so they can produce more mitochondria.
Regenancy believes it's a mitochondrial transport issue down the nerve tissue and their compound resolves the "blockage" of this pathway. (Note that a winsantor study also noticed that their drug also improved this transport mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029366/)
Disarm discovered how the body is executing axons. If they can attenuate this, they can stop the destruction. Google SARM1.
To me, this is all super exciting. Winsantor thinks they'll release in the US in 2023. Not sure on the others. But it feels like a sea change is coming for many neuropathy sufferers.
Imagine going to your neuro and getting a fix instead of pain medications?
So instead of just pain drugs, there are medications that are in human trials for nerve regrowth and (maybe) more to come.
Winsantor, Regenancy, Disarm all believe neuropathy is caused mitochondria dysfunction in nerves. There are different processes driving it (chemotherapy, HIV, diabetes and even some types of CMT) but they all seem to cause nerve destruction in a similar way.
Winsantor's drug attenuates a constraint that peripheral nerves operate under so they can produce more mitochondria.
Regenancy believes it's a mitochondrial transport issue down the nerve tissue and their compound resolves the "blockage" of this pathway. (Note that a winsantor study also noticed that their drug also improved this transport mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029366/)
Disarm discovered how the body is executing axons. If they can attenuate this, they can stop the destruction. Google SARM1.
To me, this is all super exciting. Winsantor thinks they'll release in the US in 2023. Not sure on the others. But it feels like a sea change is coming for many neuropathy sufferers.
Imagine going to your neuro and getting a fix instead of pain medications?
happydays, great informative post, I wasn’t aware of the 4th company Topiramate. I wouldn’t be surprised if more pharma become involved once they realize the large population who suffer with this disease which finally seems to be gaining attention. I think neuropathy is similar to fibromyalgia was 20 yrs. ago when dr.’s often didn’t seem to have a clue. Helen
So instead of just pain drugs, there are medications that are in human trials for nerve regrowth and (maybe) more to come.
Winsantor, Regenancy, Disarm all believe neuropathy is caused mitochondria dysfunction in nerves. There are different processes driving it (chemotherapy, HIV, diabetes and even some types of CMT) but they all seem to cause nerve destruction in a similar way.
Winsantor's drug attenuates a constraint that peripheral nerves operate under so they can produce more mitochondria.
Regenancy believes it's a mitochondrial transport issue down the nerve tissue and their compound resolves the "blockage" of this pathway. (Note that a winsantor study also noticed that their drug also improved this transport mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029366/)
Disarm discovered how the body is executing axons. If they can attenuate this, they can stop the destruction. Google SARM1.
To me, this is all super exciting. Winsantor thinks they'll release in the US in 2023. Not sure on the others. But it feels like a sea change is coming for many neuropathy sufferers.
Imagine going to your neuro and getting a fix instead of pain medications?
Hello @sidemounts, You will notice that we moved your post to an existing discussion on the same topic - Has anyone used MLS Laser therapy or Calmare Therapy?. If you click the VIEW & REPLY button at the bottom of the email notification for this post, it will take you to the discussion where you can meet other members who have shared their experience with MLS Laser or Calmare Therapy.
@mikween@caf132@mamie@laurabond79 and others have posted in various discussions about MLS Laser Therapy and may be able to share their experience with you.
I had cold laser therapy and it helped immensely, 2x week for 4 weeks is recommended. Hope what you choose works!
Will explain more of what I do if you would like.
I had cold laser therapy and it helped immensely, 2x week for 4 weeks is recommended. Hope what you choose works!
Will explain more of what I do if you would like.
Connect
Connect
Like
Helpful
Hug
There are others besides Winsantor in phase 2+ trials for drugs that stimulate peripheral nerve growth.
* Topiramate is in a phase 2 trial for people. At least one pubmed study showed it increased small fiber nerve density. (https://clinicaltrials.gov/ct2/show/NCT02878798). One of the studies is here (https://pubmed.ncbi.nlm.nih.gov/21437113/)
* A company called Regenancy is in phase 2 trials with something called an HDAC6 inhibitor. They believe it may work for many types of neuropathy. (https://regenacy.com/#our-pipeline)
* Eli Lilly is behind a venture which believes they know the biological mechanism that our bodies use to destroy axons. They're working on inhibitors. https://www.disarmtx.com/approach/
So instead of just pain drugs, there are medications that are in human trials for nerve regrowth and (maybe) more to come.
Winsantor, Regenancy, Disarm all believe neuropathy is caused mitochondria dysfunction in nerves. There are different processes driving it (chemotherapy, HIV, diabetes and even some types of CMT) but they all seem to cause nerve destruction in a similar way.
Winsantor's drug attenuates a constraint that peripheral nerves operate under so they can produce more mitochondria.
Regenancy believes it's a mitochondrial transport issue down the nerve tissue and their compound resolves the "blockage" of this pathway. (Note that a winsantor study also noticed that their drug also improved this transport mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029366/)
Disarm discovered how the body is executing axons. If they can attenuate this, they can stop the destruction. Google SARM1.
To me, this is all super exciting. Winsantor thinks they'll release in the US in 2023. Not sure on the others. But it feels like a sea change is coming for many neuropathy sufferers.
Imagine going to your neuro and getting a fix instead of pain medications?
-
Like -
Helpful -
Hug
4 Reactionshappydays, great informative post, I wasn’t aware of the 4th company Topiramate. I wouldn’t be surprised if more pharma become involved once they realize the large population who suffer with this disease which finally seems to be gaining attention. I think neuropathy is similar to fibromyalgia was 20 yrs. ago when dr.’s often didn’t seem to have a clue. Helen
-
Like -
Helpful -
Hug
4 Reactions@happydaysareahead Dare I hope? I hadn’t heard anything about this
Has anyone had the MLS laser treatment for neuropathy yet?
What is the MSL laser treatment?
A blue laser applied to feet. I think it takes some 24 treatments and has positive reviews
Hello @sidemounts, You will notice that we moved your post to an existing discussion on the same topic - Has anyone used MLS Laser therapy or Calmare Therapy?. If you click the VIEW & REPLY button at the bottom of the email notification for this post, it will take you to the discussion where you can meet other members who have shared their experience with MLS Laser or Calmare Therapy.
@mikween @caf132 @mamie @laurabond79 and others have posted in various discussions about MLS Laser Therapy and may be able to share their experience with you.
-
Like -
Helpful -
Hug
1 ReactionLooking for more results of people who have used Calmare Therapy for neuropathy????
I had cold laser therapy and it helped immensely, 2x week for 4 weeks is recommended. Hope what you choose works!
Will explain more of what I do if you would like.
-
Like -
Helpful -
Hug
1 ReactionYes I would like to know more.