Thank you for this reply, I appreciate it! My husband is currently on a maintenance-type dose of single agent gemcitabine and it seems to be holding things in check for now but I will definitely be asking his oncologist about Onivyde when we see him next week in Rochester. CA 19-9 remains high (around 5000) but we are nearly three years out from his Whipple surgery and still glad to be here - hoping for many more years. Take care!