I don't know! Good question. My doc has said I can try 1/4 dose Reclast after my Tymlos and during my cancer treatment, before Tymlos, the docs were also talking about a smaller dose of Reclast. But I don't know about dosing Prolia, sorry! Tymlos is daily so ramping up is done over days or maybe two weeks. But Prolia is so infrequent I am not sure how ramping up could be possible. So the question really is whether a lower dose injection would be allowed and of benefit.

I asked the same questions after my pain and hair loss with Prolia and my endocrinologist said, "no"!