Tired and fatigued, achey, lost libido seem to be common side effects for all of us. Sometimes the pain in my arms just kills me, it hurts a lot. I'm tired a lot also. We're not marines, we don't just "push by the pain". That's not in our paygrade. Perhaps we should be looking at alternatives to assist with our ailments. I know that Mayo has done some research on TCH and CBD. Those, and similar, chemicals appear to have promise in many, many areas and not just the old uses of getting you high. We need to open our eyes and think out of the box. It may be possible to take Lupron AND avoid it's nasty side effects. If not avoid them perhaps alleviate some of them. Quality of life is important. To have life with misery and pain is not really having a life. At least not in my line of thinking. There are alternatives, we just need to find them. Does anyone in this forum have information on pain management beyond aspirin? I'm tired of hearing take one and call me in the morning.