@irr4et - I read your post where you mentioned that pain causes 24/7 rise in cortisol. That’s exactly what I have been saying and nobody understands- not even my doctors. It lasted several years for me because of constant intestinal pain or discomfort. The result has become extreme fatigue - such as in burnout- and my old energy will never return.
I also have IBS and also suffered years of pain from an unusual GI autoimmune illness in addition to another rare illness- MALS (restricted intestinal blood flow causing extreme pain with eating).
Writing this I’m getting quite emotional and angry that it took so many years to get diagnosed.