@nimalw & JK I had a pancreas transplant in 2005. The transplant center I went to had a protocol to avoid steroids. I was originally on Cellcept & Prograf (Mycophenolate & Tacrolimus). I had issues with Cellcept and it was changed to Rapamune (Sirolimus). When the change happened I remember being brought into clinic for an IV infusion of a steroid medication (I’ve forgotten the name). It was a one time thing and I’ve not had prednisone or any other steroid before or since then.