I have had very little reaction, mainly a couple of days just being tired, and I’ve had 3 doses. I plan on getting the fourth next month. I am a transplant patient on Cellcept, tacrolimus, and Prednisone. Although the vaccine won’t entirely prevent someone from getting Covid, it will prevent a severe complication requiring hospitalization and time on a ventilator in the ICU or death. The vast majority of hospitalized patients are those not vaccinated. My son chose not to be vaccinated because he has chronic Lyme disease and wound up very, very sick. He had a doctor that does home visits so he had infusions at home. Thankfully he’s recovering.