The nodules/tumors was found by accident. I was in a auto accident 1 year after my transplant. the accident broke my neck . C6 and C7 shattered. I had brackets and screws put in to hold my head on. the MRI and CT scan after the emg. surgery showed the lesions on my spinal cord and noticed tumors in my lungs. So to anwer the Question you had. Yes I am in a lot of discomfort. I am working with palliative care. Pain Management was not able to help. I have some relief from Meds but i am limited due to the transplant.